How PCO Technology is Proven to Not Affect Plant and Animal Cells

Scientific Evidence Shows PCO Purification Works Without Impacting Biological Tissues

When evaluating air purification technologies, it’s important to consider not only performance but also compatibility with everyday indoor life. Puraclenz’s patented PCO (Photocatalytic Oxidation) purification is backed by extensive research—including studies that expose living cells to real-world levels of purification over extended time periods. The results are clear: PCO purification reduces airborne and surface pollutants while showing no observable effects on plant or animal cells.

Research-Backed Confidence in PCO Purification

Two recent peer-reviewed studies evaluated ozone free PCO and advanced photohydrolysis systems in both animal and clinical settings:

• Murine Study Published in PLOS ONE (2024): Mice were exposed continuously for 90 days to levels of Advanced Photohydrolysis used in indoor purification. Throughout the study, researchers observed normal food consumption, weight gain, and behavior. Blood chemistry and respiratory tissue structure were unchanged, with no signs of irritation or cellular damage. The study concluded that the purification process did not affect biological tissues.
  Read the full study
• Clinical Study Published in the American Journal of Infection Control (AJIC, 2024): PCO purification systems were installed in hospital ICUs while rooms remained occupied. After four months, researchers observed up to 99% reduction in mold ¹, bacteria ³, and fungal allergens ¹ on surfaces and in the air. The purification technology operated continuously with no interruptions or observable effects on the hospital environment.
  View the AJIC publication

Puraclenz PCO: Engineered for Everyday Environments

Puraclenz devices use a patented UV-C and titanium dioxide matrix to generate trace ions and oxidative molecules. These work mid-air and on surfaces to deactivate pollutants including mold ¹, mildew ¹, viruses ², and bacteria ³. Unlike other systems, Puraclenz does not rely on ozone, formaldehyde, or chemicals that can trigger sensitivity in living systems.

Independent Testing Confirms No Harmful Byproducts

Puraclenz purification has been tested in certified labs and clinical facilities to confirm:

• Zero ozone emissions (UL2998 certification)
• No generation of harmful VOCs or ultrafine particles
• Compatible for continuous use in occupied spaces, including where plants and animals are present

Proven Results With No Impact on Living Cells

These independent studies confirm that Puraclenz PCO purification can reduce indoor pollutants while remaining biologically neutral. Whether used in homes, offices, or hospitals, the purification process has been proven to not affect living cell systems.

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Sources & Further Reading

• Selitrennikoff, C.P. et al. (2024). Evaluate the safety of a novel photohydrolysis technology used to clean and disinfect indoor air: A murine study. PLOS ONE | https://doi.org/10.1371/journal.pone.0307031
• Trosch, K. et al. (2024). The effects of a novel, continuous disinfectant technology on MRSA, fungi, and aerobic bacteria in intensive care units. American Journal of Infection Control | https://doi.org/10.1016/j.ajic.2024.03.013
• Song, W. et al. (2005). Mechanistic and toxicity studies of the photocatalytic oxidation of microcystin-LR. PDF | SciSpace
• Siddiqui, S. et al. (2022). Exposure to low levels of titanium dioxide nanoparticles promotes plant growth through gibberellin pathways. Scientific Reports | https://www.nature.com/articles/s41598-022-23179-9
• Kim, S.-W. et al. (2020). Photocatalytic inactivation of plant pathogenic bacteria using TiO₂. PMC | https://pmc.ncbi.nlm.nih.gov/articles/PMC7558638/
• Palma, E. et al. (2014). Photocatalysis and cell membrane integrity in yeast: A microbiological safety evaluation. PMC | https://pmc.ncbi.nlm.nih.gov/articles/PMC4249241/
• Lu, H. et al. (2024). Review on photocatalytic applications for deodorization in livestock and poultry farms. Agriculture (MDPI) | https://www.mdpi.com/2077-0472/14/12/2216
• Navarrete, C. et al. (2023). Human health risk assessment of benzene, toluene, ethylbenzene, and xylene oxidation by TiO₂/volcanic glass. Molecules (MDPI) | https://www.mdpi.com/1420-3049/28/24/8119
• Zuraimi, M.S. & Tham, K.W. (2021). Performance and byproduct review of ultraviolet photocatalytic oxidation in HVAC systems. Journal of Hazardous Materials | https://www.sciencedirect.com/science/article/abs/pii/S0304389421017313

At the heart of all Puraclenz purifiers is our patented Recharge Cell that cleans your space with ions. Laboratory tests against pollutants were conducted with a model P3000 unit that uses the same Recharge Cell that powers all Core and Photon purifiers. Recharge Cell (model R0002) powers all Puraclenz purifiers (models C750, P3000X, P3000, P1500, and P750).

¹ In independent laboratory testing, the Photon purifier was 99.75% effective at reducing Candida albicans from surfaces and 95.1% effective at reducing Aspergillus brasiliensis in the air.

² In independent laboratory testing, the Photon purifier was 99.4% effective at reducing MS2 bacteriophage virus in the air and 58% effective at reducing SARS-CoV-2 on surfaces.

³ In independent laboratory testing, the Photon purifier was 99.7% effective at reducing dangerous bacteria Methicillin-Resistant Staphylococcus epidermidis in the air and 95% effective at reducing dangerous bacteria Staphylococcus aureus on surfaces.

⁴ Non-living sources such as pet dander, cockroach matter allergens, dust mite matter allergens.